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Optiminization of regeneration at the stages of soft tissue augmentation using a collagen matrix

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Lack of adequate width and thickness of periodontal or peri-implant soft tissues can compromise the aesthetics, function or survival of teeth and dental implants. Biomaterials are widely used in dentistry to overcome the disadvantages of autogenous tissue transplantation. The advantage of using biomaterials is that there is no need for re-surgery and that they are available in large quantities. The most widely used biomaterial for soft tissue augmentation is collagen, as it is believed to best mimic the natural cellular environment of the extracellular matrix, although other biomaterials are also candidates for soft tissue regeneration. Collagen matrices differ in composition, three-dimensional structure, elasticity and mechanical stability. Aim. is to review the literature on the optimization of regeneration at the stages of soft tissue augmentation using a collagen matrix.

Об авторах

А. B. Adzhieva
“Peoples' Friendship University of Russia” (RUDN University)

Postgraduate student


I. А. Voronov
“Peoples' Friendship University of Russia” (RUDN University)

Doctor of Medical Sciences, Professor of the Department of Prosthodontic


S. S. Ivanov
“Peoples' Friendship University of Russia” (RUDN University)

Postgraduate student


N. М. Nalchajyan
“Peoples' Friendship University of Russia” (RUDN University)

Postgraduate student


Список литературы

1. Frizzera F, Oliveira GJPL, Shibli JA, Moraes KC, Marcantonio EB, Marcantonio Junior E. Treatment of peri-implant soft tissue defects: a narrative review. Braz Oral Res. 2019; 33 (suppl 1):e073. Published 2019 Sep 30. doi:10.1590/1807-3107bor-2019.vol33.0073.

2. Bouri Jr A, Bissada N, Al-Zahrani MS, Faddoul F, Nouneh I. Width of keratinized gingiva and the health status of the supporting tissues around dental implants. Int J Oral Maxillofac Implants 2008; 23:323–6.

3. Zweers, Jeroen & Thomas, R. & Slot, Dagmar & Weisgold, Arnold & Weijden, G. (2014). Characteristics of periodontal biotype, its dimensions, associations and prevalence: A systematic review. Journal of clinical periodontology.

4. Chiu Y W, Lee SY, Lin YC, Lai YL. Significance of the width of keratinized mucosa on peri-implant health. J Chin Med Assoc. 2015;78(7):389-394.

5. Moraschini V, Luz D, Velloso G, Barboza EDP. Quality assessment of systematic reviews of the significance of keratinized mucosa on implant health. Int J Oral Maxillofac Surg. 2017;46(6):774-781.

6. Deeb JG, Bencharit S, Loschiavo CA, Yeung M, Laskin D, Deeb GR. Do Implant Surgical Guides Allow an Adequate Zone of Keratinized Tissue for Flapless Surgery?. J Oral Maxillofac Surg. 2018;76(12):2540- 2550.

7. Roccuzzo M, Grasso G, Dalmasso P. Keratinized mucosa around implants in partially edentulous posterior mandible: 10-year results of a prospective comparative study. Clin Oral Implant Res. 2016;27(4):491- 496.

8. S.I. Bulanov, A.D. Lysov, M.V. Sofronov. Rationale for the use of connective tissue autograft in dental implantation. Bulletin of Medical Institute "Reaviz": Rehabilitation, Doctor and Health. 2017; 5(29): 81-94.

9. S.M. Kutepov, E.A. Volokitina, M.V. Gilev, Yu.V. Antoniadi, E.V. Pomogaeva. Augmentation of bone defects of the distal tibia with synthetic b-tricalcium phosphate and xenoplastic material "Osteomatrix" in surgical treatment of intraarticular impingement fractures. Genius Orthopedics. 2016. № 3:14-20.

10. M.D. Perova, N.V. Lapina, E.A. Fomicheva, V.B. Karpyuk, A.V. Tropina, A.A. Vziatyshev . Evaluation of autotransplantation of connective tissue palatal flap in combination with vascular-stromal-cell fraction of lipoaspirate in tissue recession (10 years of observations). Russian Journal of Stomatology; 2016. 20 (5):260-266.

11. Types of gingival grafts and their use in periodontal dentistry. E.V. Antipova, O.Yu. Ponomarev. Periodontology. 2016; Т. 21; 2(79): 24-28.

12. L.F. Razheva, V.A. Kravchenko, V.G. Shchulzhenko, N.N. Yakimov. Transplantation operation of full-layer mucosal graft from the area of hard palate. Healthcare of the Far East. 2013; 2(56):107-111.

13. Thoma, D.S.; Zeltner, M.; Hilbe, M.; Hammerle, C.H.; Husler, J.; Jung, R.E. Randomized controlled clinical study evaluating effectiveness and safety of a volume-stable collagen matrix compared to autogenous connective tissue grafts for soft tissue augmentation at implant sites. J. Clin. Periodontol. 2016; 43, 874–885.

14. Thoma, D.S.; Nanni, N.; Benic, G.I.; Weber, F.E.; Hammerle, C.H.; Jung, R.E. Effect of platelet-derived growth factor-BB on tissue integration of cross-linked and non-cross-linked collagen matrices in a rat ectopic model. Clin. Oral Implants Res. 2015, 26, 263–270.

15. Ferrantino, L.; Bosshardt, D.; Nevins,M.; Santoro, G.; Simion,M.; Kim, D. Tissue Integration of a Volume-Stable Collagen Matrix in an Experimental Soft Tissue Augmentation Model. Int. J. Periodont. Restor. Dent. 2016, 36, 807–815.

16. Mathes, S.H.; Wohlwend, L.; Uebersax, L.; von Mentlen, R.; Thoma, D.S.; Jung, R.E.; Gorlach, C.; Graf-Hausner, U. A bioreactor test system to mimic the biological and mechanical environment of oral soft tissues and to evaluate substitutes for connective tissue grafts. Biotechnol. Bioeng. 2010, 107, 1029–1039.

17. Zeltner, M.; Jung, R.E.; Hammerle, C.H.; Husler, J.; Thoma, D.S. Randomized controlled clinical study comparing a volume-stable collagen matrix to autogenous connective tissue grafts for soft tissue augmentation at implant sites: Linear volumetric soft tissue changes up to 3 months. J. Clin. Periodontol. 2017, 44, 446–453.

18. Thoma, D.S.; Naenni, N.; Benic, G.I.; Hammerle, C.H.; Jung, R.E. Soft tissue volume augmentation at dental implant sites using a volume stable three-dimensional collagen matrix–Histological outcomes of a preclinical study. J. Clin. Periodontol. 2017, 44, 185–194.

19. Caballé-Serrano J, Zhang S, Ferrantino L, Simion M, Chappuis V, Bosshardt DD. Tissue Response to a Porous Collagen Matrix Used for Soft Tissue Augmentation. Materials (Basel). 2019;12(22):3721. Published 2019 Nov 11. doi:10.3390/ma12223721.

20. Vallecillo C, Toledano-Osorio M, Vallecillo-Rivas M, Toledano M, Osorio R. In Vitro Biodegradation Pattern of Collagen Matrices for Soft Tissue Augmentation. Polymers (Basel). 2021;13(16):2633. Published 2021 Aug 7. doi:10.3390/polym1316263.

Для цитирования:

Adzhieva А.B., Voronov I.А., Ivanov S.S., Nalchajyan N.М. Optiminization of regeneration at the stages of soft tissue augmentation using a collagen matrix. Эндодонтия Today. 2021;19(4):317-319.

For citation:

Adzhieva A.B., Voronov I.A., Ivanov S.S., Nalchajyan H.M. Optiminization of regeneration at the stages of soft tissue augmentation using a collagen matrix. Endodontics Today. 2021;19(4):317-319.

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