Dynamics of blood osteomarkers in the treatment of generalized periodontitis
https://doi.org/10.36377/ET-0021
Abstract
AIM. Study of the dynamics of bone metabolism in the treatment of generalized periodontitis.
MATERIALS AND METHODS. 60 patients with chronic generalized periodontitis of moderate to severe severity were examined and treated. A group of 15 healthy individuals without periodontal disease served as a control group. To assess the dynamics of bone formation, blood parameters were measured for bone metabolism: osteocalcin levels, alkaline phosphatase levels, and β-CrossLaps levels. Densitometry of the proximal femoral and lumbar spine regions was also performed.
RESULTS. The study revealed increased bone metabolism compared with the control group, an increase in bone metabolism activity was found 3 months after treatment of patients with chronic generalized periodontitis, and after 12 months the values of the studied parameters did not differ from the control group.
CONCLUSIONS. Thus, when treating generalized periodontitis, it is necessary to use a treatment regimen that takes into account the individual mineral metabolism of the patient’s bone tissue.
About the Authors
O. A. Uspenskaya
Privolzhsky Research Medical University
Russian Federation
Competing Interests:
Russian Federation
Olga A. Uspenskaya – Dr. Sci. (Med.), Associate Professor, Head of the Department of Therapeutic Dentistry
10/1, Minina and Pozharsky Sq, Nizhny Novgorod 603000
Competing Interests:
The authors declare no conflict of interests.
E. S. Kachesova
Privolzhsky Research Medical University
Russian Federation
Competing Interests:
Russian Federation
Evgenia S. Kachesova – Cand. Sci. (Med.), Associate Professor of the Department of Therapeutic Dentistry
10/1, Minina and Pozharsky Sq, Nizhny Novgorod 603000
Competing Interests:
The authors declare no conflict of interests.
A. I. Mednikova
Privolzhsky Research Medical University
Russian Federation
Competing Interests:
Russian Federation
Alina I. Mednikova – Student
10/1, Minina and Pozharsky Sq, Nizhny Novgorod 603000
Competing Interests:
The authors declare no conflict of interests.
R. A. Ftoyan
Privolzhsky Research Medical University
Russian Federation
Competing Interests:
Russian Federation
Rimma A. Ftoyan – Student, Privolzhskiy Research Medical University
10/1, Minina and Pozharsky Sq, Nizhny Novgorod 603000
Competing Interests:
The authors declare no conflict of interests.
References
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Review
For citations:
Uspenskaya O.A., Kachesova E.S., Mednikova A.I., Ftoyan R.A. Dynamics of blood osteomarkers in the treatment of generalized periodontitis. Endodontics Today. 2024;22(2):162-166. (In Russ.) https://doi.org/10.36377/ET-0021
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