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Antimicrobial efficacy of ozone therapy in endodontic treatment: A systematic review

https://doi.org/10.36377/ET-0073

Abstract

AIM. The objective was to assess whether endodontic treatment using ozone therapy improves the antimicrobial efficacy in patients undergoing root canal treatment.
MATERIALS AND METHODS. Electronic search on various data sources like pubmed, Scopus, Web of science and Google scholar along with hand searching of the articles in Institutional library was done. Studies comparing the results of ozone used as irrigant and intracanal medicament with conventional root canal irrigants in improving the disinfection and antimicrobial effect were eligible for this review. The study designs published were comparative in-vitro studies, randomized controlled trials, controlled clinical trials, experimental studies, and cohort studies between 1st January 2018 and 31st March 2023 Studies in English language or those possible of getting translated into English language were included. The studies including intervention using ozone therapy as irrigant and intracanal medicament and comparison with conventional root canal irrigant were included. The primary search yielded a total of 144 studies from various search engines mentioned above,74 studies were excluded based on screening titles. After screening the remaining 70 articles for abstract and full text, final 6 studies were selected for the review and remaining 64 duplicated articles were excluded.
RESULTS. The ozone therapy has a significant impact in reducing colony forming units and thus can be used as an adjunct to root canal irrigant and thus has better antibacterial properties over conventional root canal irrigating solutions.

About the Authors

P Doshi
D.Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth
India

Purva Doshi – Postgraduate Student in Department of Conservative Dentistry and Endodontics

Pimpri, Pune, Maharashtra


Competing Interests:

The authors report no conflict of interest.



P Oswal
D.Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth
India

Piyush Oswal – Associate Professor in Department of Conservative Dentistry and Endodontics

Pimpri, Pune, Maharashtra


Competing Interests:

The authors report no conflict of interest.



S. R. Srinidhi
D.Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth
India

Surya Raghavendra Srinidhi – Professor and Head in Department of Conservative Dentistry and Endodontics

Pimpri, Pune, Maharashtra


Competing Interests:

The authors report no conflict of interest.



M. Bhujbal
D.Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth
India

Mayuresh Bhujbal – Postgraduate Student in Department of Conservative Dentistry and Endodontics

Pimpri, Pune, Maharashtra


Competing Interests:

The authors report no conflict of interest.



K. Malu
D.Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth
India

Krutika Malu – Postgraduate Student in Department of Conservative Dentistry and Endodontics

Pimpri, Pune, Maharashtra


Competing Interests:

The authors report no conflict of interest.



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Review

For citations:


Doshi P., Oswal P., Srinidhi S.R., Bhujbal M., Malu K. Antimicrobial efficacy of ozone therapy in endodontic treatment: A systematic review. Endodontics Today. 2025;23(1):80-87. https://doi.org/10.36377/ET-0073



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