Histological and histomorphometric investigation of SiO2 nanoparticle-coated PEEK implants on the osseointegration in rabbit
https://doi.org/10.36377/ET-0169
Abstract
INTRODUCTION. Metal, polymer, and ceramic implants are examples of biocompatible implants that are frequently suggested to enhance osseointegration and promote bone formation. The goal of this study was to improve osseointegration by developing a new interface. This contact exists between bone tissue and the polymeric component. Silicon dioxide material is applied to PEEK (polyether ether ketone) plastic in this work coat.
MATERIALS AND METHODS. Thirty New Zealand rabbits received sixty implants. Each rabbit has two implants in its tibia. Ten rabbits were scarified at two, four and six, weeks following implantation. The left tibia implant was experimental (coated with silicon dioxide), while the right tibia implant was control (uncoated) for every animal. Following hematoxylin and eosin staining, each section was histologically inspected and evaluated for histomorphometric analysis to count bone cells (osteoblast, osteocyte, and osteoclast) and the area of new bone is formed.
RESULTS. In comparison to control groups, histological results for silicon dioxide-coated PEEK implants showed a more rapid of bone growth, mineralization, and maturation. Significant difference of histomorphometric examination of every bone parameter was very high between the control and experimental groups during the course of all healing intervals.
CONCLUSIONS. According to the current study, the nano-silicon dioxide coating promotes faster osseointegration than an uncoated implant, improving bone formation and increasing the healing rates.
About the Authors
Y. M. Haider
University of Baghdad
Iraq
Competing Interests:
Iraq
Yagthan Mohammed Haider – Lecturer, Department of Prosthodontic, College of Dentistry
Baghdad, Iraq
Competing Interests:
The authors report no conflict of interest.
G. H. Jani
University of Baghdad
Iraq
Competing Interests:
Iraq
Ghasak H. Jani – Assistant Professor, Department of Prosthodontic, College of Dentistry
Baghdad, Iraq
Competing Interests:
The authors report no conflict of interest.
A. A. Fatalla
University of Baghdad
Iraq
Competing Interests:
Iraq
Abdalbseet A. Fatalla – Professor, Department of Prosthodontic, College of Dentistry
Baghdad, Iraq
Competing Interests:
The authors report no conflict of interest.
R. A. Mohammed
University of Baghdad
Iraq
Competing Interests:
Iraq
Raghad Abdullrazzaq Mohammed – Professor, Department of Conservative, College of Dentistry
Baghdad, Iraq
Competing Interests:
The authors report no conflict of interest.
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Review
For citations:
Haider Y.M., Jani G.H., Fatalla A.A., Mohammed R.A. Histological and histomorphometric investigation of SiO2 nanoparticle-coated PEEK implants on the osseointegration in rabbit. Endodontics Today. 2026;24(1):136-142. https://doi.org/10.36377/ET-0169
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