Evaluation of the effectiveness of treatment of chronic apical periodontitis with the use of high-intensity laser irradiation and platelet autoplasma

Aim. The pathological process in the periodontal with chronic apical periodontitis is actively supported by optional and obligatory anaerobic microflora. The purpose was to improving the quality of endodontic treatment of chronic apical periodontitis using high-intensity laser radiation and injecting platelet autoplasma.

Material and methods. We observed 55 young patients with chronic apical periodontitis of multi-rooted teeth of the upper and lower jaw without endodontic intervention. The method proposed by us was based on the qualitative decontamination of the root canal system in chronic apical periodontitis using a diode laser and injection injection of platelet-rich autoplasma. The following research methods were used: densitometric and microbiological.

Results. Microbiological methods established the elimination of enterococci, β-hemolytic staphylococci, facultative anaerobic cocci, Gr+ sticks, yeast-like fungi of the genus Candida. Suppression of growth of facultative-anaerobic and obligate-anaerobic microflora, reduction of occurrence of γ and λ hemolytic streptococci, fusobacteria, Bacteroides. The complex has a pronounced antibacterial and anti-inflammatory effect. The use of autologous plasma increases the optical density of bone tissue in the periapical region of the chewing groups of the teeth of the upper and lower jaw. It has been established that the use of a diode laser and injection injection of platelet autoplasma in the treatment of chronic apical periodontitis in the dynamics of observation is effective and reasonable. 

1. Demyanenko S. A., Tofan Yu. V., Tkachenko I. M. Modern aspects of treatment of chronic apical periodontitis // Bulletin of problems of biology and medicine. 2018. T. 1. №4 (146). P. 254-257. DOI:10.29254/2077-4214-2018-4-1-146-254-258.

2. Demyanenko S. A., Tofan Yu. V. Modern views on the application of platelet-rich blood plasma of the endodontic treatment of chronic apical periodontitis // Crimean therapeutic magazine. 2018. №3. P. 7-11.

3. Manak T. N., Savostikova O. S., Mitronin A. V. Wettability analysis of solutions for endodontic irrigation // Endodontics Today. 2018. №4. P. 28-31. DOI: 10.25636/PMP.2.2018.4.7.

4. Manucharyan, L. A., Mitronin A. V., Ippolitov E. V. Characterization of effects of diode laser low power on test strains of microorganisms in the in vitro experiment with photoactivatable disinfection system // Endodontics Today. 2014. №1 (29). P.43-45.

5. Mitronin A. V., Belyaeva T. S., Zhekova A. A. Laser technologies in endodontic treatment of chronic apical periodontitis: comparative evaluation of antibacterial effectiveness // Endodontics Today. 2016. №2. P. 27-29.

6. Mitronin A. V., Belyaeva T. S., Zhekova A. A. Evaluation of the effectiveness of diode laser and photoactivated therapy in endodontic treatment // Dentistry. 2016. Vol. 95. №6-2. P. 15-16.

7. Orekhova L. J., Dudareva, L. A., Berezkinа, V. I. Comparative characteristics of informative value of various methods of radiodiagnosis // Periodontics. 2008. No. 3. P. 48-50.

8. Chibisova M. A., Dudarev A. L., Batyukov N. M. Optimization of diagnosis and treatment of chronic periodontitis of teeth using dental computed tomography // Endodontics today. 2012. Vol. VI. №1-2. P. 63-74.

9. Sorokin A. P., Gerasimova L. P. Optical densitometry of the periapical region according to radiovisiography and dental computed tomography // Practical medicine. 2013. №5 (71). P. 150-153.

10. Yusupovа A. F., Gerasimova L. P., Usmanova I. N., Sorokin, A. P. Comparative characteristic of standards of the optical density of bone tissue in the periapical region at persons of young age // Endodontics Today. 2018. №3. P. 35-38. DOI: 10.25636/10.25636/PMP.2.2018.3.8.

11. Hommez G. M., Meerleer G. O. De, Neve W. J. De, Moor R. J. De. Effect of radiation dose on the prevalence of apical periodontitis-a dosimetric analysis // Clin. Oral Investig. 2012. Vol. 16. №6. P. 15431547. DOI: 10.1007/s00784-011-0665-1.

12. Pereira C. A., Romeiro R. L., Costa A. C. et al. Susceptibility of Candida albicans, Staphylococcus aureus, and Streptococcus mutans biofilms to photodynamic inactivation: an in vitro study // Lasers Med. Sci. 2011. Vol. 26. №3. P. 341-348. DOI: 10.1007/s10103-010-0852-3.

13. Yu V. S., Khin L. W., Hsu C. S. et al. Risk score algorithm for treatment of persistent apical periodontitis // J. Dent. Res. 2014. Vol. 93. №11. P. 1076-1082. DOI: 10.1177/0022034514549559.