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Clinical and biochemical assessment of the state of oral tissue in patients with paranoid schizophrenia of continuous flow

https://doi.org/10.25636 / PMP.2.2018.3.3

Abstract

Research objective. To assess the state of oral tissue in patients with paranoid schizophrenia of continuous flow according to biochemical indices of mixed saliva and to compare with clinical parameters. Material and methods. 57 patients with continuous paranoid schizophrenia were divided into 5 groups according to age. The rate of salivation, pH was calculated, the activity of AST, ALT, APF, LDH, total protein, IL-1β, —4, —6, —10, TNF-α was determined in saliva. All the results obtained were processed by variational statistics, correlation analysis by Spearmen. Results and discussion. Patients with paranoid schizophrenia of the continuous course revealed an unfavorable clinical status of the oral tissues, which correlates with the parameters of mixed saliva.

About the Authors

N. E. Dukhovskaya
ФГБОУ ВО МГМСУ им. А. И. Евдокимова Минздрава РФ.
Russian Federation


S. V. Abramov
ГБУЗ МО «Центральная клиническая психиатрическая больница».
Russian Federation


T. P. Vavilova
ФГБОУ ВО МГМСУ им. А. И. Евдокимова Минздрава РФ.
Russian Federation


Yu. A. Mitronin
ФГБОУ ВО МГМСУ им. А. И. Евдокимова Минздрава РФ.
Russian Federation


Yu. A. Ostrovskаyа
ФГБОУ ВО МГМСУ им. А. И. Евдокимова Минздрава РФ.
Russian Federation


A. A. Dukhovskaya
ФГБОУ ВО МГМСУ им. А. И. Евдокимова Минздрава РФ.
Russian Federation


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Review

For citations:


Dukhovskaya N.E., Abramov S.V., Vavilova T.P., Mitronin Yu.A., Ostrovskаyа Yu.A., Dukhovskaya A.A. Clinical and biochemical assessment of the state of oral tissue in patients with paranoid schizophrenia of continuous flow. Endodontics Today. 2018;16(3):13-17. (In Russ.) https://doi.org/10.25636 / PMP.2.2018.3.3



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