Preview

Endodontics Today

Advanced search

Cell reaction of the primary teeth pulp after pulpotomy treatment with different medicines

Abstract

243 primary teeth in 112 children aged 3-8 years were treated using pulpotomy. The medicines «Pulpotek», «Trioxident» and «Viskosta» in combination with Zinkoxid Eugenol were used to cover the pulp stump. The reaction of immunocompetent cells of the teeth pulp to the above-mentioned medicines was studied in 48 teeth. 12 months later, after the treatment of pulpitis with Pulpotek and Viskostat combined with Zinkoxid Eugenol, the level IL 1β and TNF-α in the samples of the pulp tissue had no significant difference comparing with the normal index. There was no normalization of the pulp tissues in 33,3% of cases of pulpitis treatment with Trioxident that proved a decrease of the IL 1β level and an increase of that of TNF-α in the samples of the pulp tissues extracted after using this method

About the Authors

Т.П. Вавилова
ГБОУ ВПО МГМСУ им. А.И. Евдокимова Минздрава России
Russian Federation


И.Г. Островская
ГБОУ ВПО МГМСУ им. А.И. Евдокимова Минздрава России
Russian Federation


Л.П. Кисельникова
ГБОУ ВПО МГМСУ им. А.И. Евдокимова Минздрава России
Russian Federation


И.С. Щербина
ГБОУ ВПО МГМСУ им. А.И. Евдокимова Минздрава России
Russian Federation


References

1. Вавилова Т. П., Островская И. Г. Биохимия и физиология пульпы зуба. Монография. - М.: Изд-во Медиа-Сфера, 2008. - 136 с.

2. Кисельникова Л. П., Гончарова С. В., Кочеткова О. А. Методы лечения пульпита временных зубов // Институт стоматологии. 2002. №4. С. 28-29.

3. Елизарова В. М., Персин Л. С., Дьякова С. В. и соавт. Стоматология детского возраста. - М.: Медицина, 2003 - 640 с.

4. Боровский Е. В. Проблемы эндодонтического лечения // Клиническая стоматология. 1997. №1. С. 5-8.

5. Боровский Е. В., Свистунова И. А., Кочергин В. Н. Да или нет резорцин-формалиновому методу // Клиническая стоматология. 1997. №3. С. 16-18.

6. Fuks A. B. Vital pulp therapy with new materials for primary teeth: new directions and treatment perspectives // J Endod. 2008. Jul. №34 (7 Suppl). Р. 18-24.

7. Bletsa A., Heyeraas K. J., Haug S. R., Berggreen E. IL-1 alpha and TNF-alpha expression in rat periapical lesions and dental pulp after unilateral sympathectomy // Neuroimmunomodulation. 2004. Vol. 11. P. 376-384.

8. Nedrebø T., Berg A., Reed R.K. Effect of tumor necrosis factoralpha, IL-1beta, and IL-6 on interstitial fluid pressure in rat skin // Am. J. Physiol. 1999. Vol. 277 (5 Pt 2). P. 1857-1862.

9. Bowen J. L., Mathu-Muju K. R., Nash D. A., Chance K. B., Bush H. M., Li H. F. Pediatric and general dentists’ attitudes toward pulp therapy for primary teeth // Pediatr Dent. 2012. May-Jun. №34 (3). Р. 210-215.

10. Sonmez D., Sari S., Cetinbas T. A comparison of four pulpotomy techniques in primary molars: A long term followup // J Endod. 2008. №34. Р. 950-955.

11. Salako N., Joseph B., Ritwik P., Salonen J., John P., Junaid T. A. Comparison of bioactive glass, mineral trioxide aggregate, ferric sulfate and formocresol as pulpotomy agents in rat molar // Dent Traumatol. 2003. №19. Р. 314-320.

12. Cohen S. T., Burns R. Patways of the pulp. 6th edition. - St. Louis: Mosby, 1994.

13. Menezes R., Bramante C. M., Letra A., Carvalho V. G., Garcia R. B. Histologic evaluation of pulpotomies in dog using two types of mineral trioxide aggregate and regular and white Portland cements as wound dressings // Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004. №98. Р. 376-379.

14. Smith N. L., Seale N. S., Nunn M. E. Ferric sulfate pulpotomy in primary molars: A retrospective study // Pediatr Dent. 2000. №22. Р. 192-199.

15. Prabhakar A. R., Bedi S. Effect of glutaraldehyde and ferric sulfate on shear bond strength of adhesives to primary dentin // J. Indian Soc Pedod Prev Dent. 2008. №26. Suppl 3. S. 109-113.

16. Godhi B., Sood P. B., Sharma A. Effects of mineral trioxide aggregate and formocresol on vital pulp after pulpotomy of primary molars: An in vivo study // Contemp Clin Dent. 2011. Oct. №2 (4). Р. 296-301.

17. Saltzman B., Sigal M., Clokie C., Rukavina J., Titley K., Kulkarni G. V. Assessment of a novel alternative to conventional formocresol-zinc oxide eugenol pulpotomy for the treatment of pulpally involved human primary teeth: diode laser-mineral trioxide aggregate pulpotomy // Int J Paediatr Dent. 2005. №15. Р. 437-447.

18. Huth K. C., Paschos E., Hajek-Al-Khatar N., Hollweck R., Crispin A., Hickel R., Folwaczny M. Effectiveness of 4 pulpotomy techniques-randomized controlled trial // J Dent Res. 2005. №84 (12). Р. 1144-1148.

19. Ranly D. M., Horn D. Assessment of the systemic distribution and toxicity of formaldehyde following pulpotomy treatment: Part two // J Dent Child. 1987. №54. Р. 40-44.

20. Lewis B. B., Chestner S. B. Formaldehyde in dentistry: A review of mutagenic and carcinogenic potential // J Am Dent Assoc. 1981. №103. Р. 429-434.


Review

For citations:


 ,  ,  ,   Cell reaction of the primary teeth pulp after pulpotomy treatment with different medicines. Endodontics Today. 2014;12(1):34-37. (In Russ.)



Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1683-2981 (Print)
ISSN 1726-7242 (Online)