Исследование содержания белков, участвующих в фосфорно-кальциевом обмене, в пульпе постоянных зубов при воспалении
Abstract
In the given work in gomogenates pulps of a constant teeth have been studied changes in the maintenance osteocalcin,
annexin V, alkaline phosphatase at a chronic pulpitis. It has been revealed that in a pulp of a tooth at an inflammation decrease
in quantity osteocalcin, alkaline phosphatase and increase in the maintenance annexin V is observed. The received
results testify to inhibition of education reparatived dentin in a pulp of a teeth at a chronic pulpitis.
annexin V, alkaline phosphatase at a chronic pulpitis. It has been revealed that in a pulp of a tooth at an inflammation decrease
in quantity osteocalcin, alkaline phosphatase and increase in the maintenance annexin V is observed. The received
results testify to inhibition of education reparatived dentin in a pulp of a teeth at a chronic pulpitis.
About the Author
И. Островская
ГОУ ВПО «Московский государственный медико-стоматологический университет Росздрава»
Russian Federation
Russian Federation
References
1. Вавилова Т. П., Островская И. Г. Биохимия и физиология пульпы зуба. - М., 2008. - 136 с.
2. Гемонов В. В., Лаврова Э. М., Фалин Л. И. Развитие и строение органов ротовой полости. - М., 2002. - С. 100-111.
3. Касабьян С. С., Рукавишникова Л. И. Механизм кальцификации и реакции клеточных элементов пульпы зуба // Стоматология. 1971. Т. 50. №2. С. 4-6.
4. Московский А. В. Периодизация механизмов биоаминной регу- ляции гисто- и органогенеза зуба // Стоматология. 2005. №11. С. 6-9.
5. Пикалюк В. С., Мостовой С. О. Современные представления о биологии и функции костной тка- ни // Таврич. медико-биол. вест. 2006. Т. 9. №3. С. 186-194.
6. Bjоrndal L., Mjör I. A. Pulpdentin biology in restorative dentistry. 4. Dental caries - Characteristics of lesions and pulpal reactions // Quintessence Int. 2001. Vol. 32. Р. 717-736.
7. Goldberg M., Smith A.J. Cells and extracellularmatrices of dentin and pulp a biological basis for repairand tissue engineering // Crit. Rev. Oral Biol. Med. 2004. Vol. 15. Р. 13-27.
8. Guo M. K., Messer H. H. A comparison of Ca2+-, Mg2+-ATPase and alkaline phosphatase activities of rat incisor pulp // Calcified Tissue International. 1978. Vol. 28. №4. С. 34-39.
9. Hillmann G., Geurtsen W. Lightmicroscopical investigation of the distribution of extracellular matrix molecules and calcifications in human dental pulps of various ages // Cell and Tissue Research. 1997. Vol. 289. №1. P. 145-154.
10. Iohara K., Nakashima M., Ito M. et al. Dentin Regeneration by Dental Pulp Stem Cell Therapy with Recombinant Human Bone Morphogenetic Protein // J. Dent. Res. 2004. №83. №8. P. 590- 595.
11. Kirsch T., Nah H.-D., Demuth D. R. et al. Annexin V-mediated calcium flux across membranes is dependent on the lipid composition. Implications for cartilage mineralization // Biochemistry. 1997. Vol. 36. P. 3359- 3367.
12. Larmas M. Odontoblast function seen as the response of dentinal tissue to dental caries // Adv. Dent. Res. 2001. Vol. 15. Р. 68-71.
13. Linde A. Dentin matrix proteins: Composition and possible functions in calcification // Anat. Rec. 1989. Vol. 224. Р. 154-166.
14. Matsumoto A. Effect of a lowcalcium environment on alkaline phosphatase activity in embryonic rat calvarial bone cells in culture // Arch. Oral Biol. 1996. Vol. 41. Р. 41-45.
15. Rashid F., Shiba H., Mizuno N., et al. The Effect of extracellular calcium ion on gene expression of bonerelated proteins in human pulp cells // JOE. 2003. Vol. 29. №2. P. 104-107.
16. Tziafas D. The future role of a molecular approach to pulp-dentinal regeneration // Caries Res. 2004. Vol. 38. P. 314-320.
Review
For citations:
. Endodontics Today. 2011;9(3):11-13. (In Russ.)
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