Changes in the oral mucosa and general indicators with COVID 19 (SARS-CoV-2): a single-center descriptive study
https://doi.org/10.36377/1683-2981-2020-18-2-4-9
Abstract
Aim. To study the state of oral mucosa and rationale of Its changes In patients with a laboratory-con^rmed diagnosis of SARS-CoV-2, moderate severity.
Materials and methods. A retrospective single-center study was conducted on patients who were In the Infectious diseases department from May to June 2020 with an Initial diagnosis of ICD-X: J18.9: coronavirus Infection. This study Included 90 patients aged 24 to 83years (52 male and 38 female, average age 53.6 ± 9.7years).
Results. C-reactIve protein was Increased In 81 Individuals upon admission (44.15 ± 31.8 mg /dl). Twenty patients had Increased tibrinogen values (average Increased tibrinogen values were 5.96 ± 1.6 g /1). The analysis for D-dImer was held In 15 patients (average value 348 ± 103.68 ng/ml), 10 people from that with the increased indicators (435 ± 24 ng / ml). Hemorrhagic manifestations occurred in 12 (13.3%) patients, whose history was not burdened. Pronounced xeroderma of the facial region and angular cheilitis were detected in 21 (23.3%) patients. In 80 patients (88.8%), an examination of the mucous membrane of the tongue was observed plaque from white, lightyellowto brown. In 36(40%) patients, pigmentation was detected in the area of the attached gingiva on the upper and lower jaws.
Conclusions. With COVID 19 (SARS-CoV-2), changes in oral mucosa are not the primary cause, but appear as a result of drug treatment and disease progression, despite the fact that the oral cavity is one of the sources of entry gates for infection.
About the Authors
Z. S. Khabadze
'"Peoples' Friendship University of Russia" (RUDN University)
Russian Federation
Russian Federation
Ph.D., Associate Professor, Department of TherapeutIc Dentistry
Moscow
K. E. Sobolev
"Krasnogorsk Municipal Hospital No. 1'
Russian Federation
Russian Federation
Head physician
Moscow
I. M. Todua
Private dental practice
Russian Federation
Russian Federation
Dentist
Moscow
O. S. Mordanov
National Medical Research Center of Dentistry and Oral and Maxillofacial Surgery
Russian Federation
Russian Federation
Resident student
Moscow
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Review
For citations:
Khabadze Z.S., Sobolev K.E., Todua I.M., Mordanov O.S. Changes in the oral mucosa and general indicators with COVID 19 (SARS-CoV-2): a single-center descriptive study. Endodontics Today. 2020;18(2):4-9. (In Russ.) https://doi.org/10.36377/1683-2981-2020-18-2-4-9
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