High resolution-1Н NMR spectroscopy of oral liquid in young patients with wedge-shaped lesions
https://doi.org/10.36377/1683-2981-2020-18-4-20-25
Abstract
Aim. The comparison of saliva 1Н NMR spectra in patients with wedge-shaped lesions before and after treatment.
Materials and methods. Saliva as a study material was taken from patients with wedge-shaped lesions before and after treatment. The treatment method was remineralizing therapy that included the use of the oral rinse containing zinchydroxyapatite. 1Н NMR spectroscopy was chosen as an investigation method.
Results. In most cases it is noted that after treatment the content of propionic and butyric acids was on the rise in relation of acetic acid. Overall concentration of 1Н protons didn't change significantly.
Conclusions. 1Н NMR spectra analysis shows organic acid distribution in oral liquid before and after treatment, which helps to evaluate its response.
About the Authors
A. V. Mitronin
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
Competing Interests: The authors declare no conflict of interests.
Russian Federation
Professor, Doctor of Medical Sciences, Dean of the Faculty of Dentistry, Head of the Department of cariology and endodontics, Honored Doctor of Russian Federation.
Moscow.
Competing Interests: The authors declare no conflict of interests.
E. A. Srebnaya
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
Competing Interests: The authors declare no conflict of interests.
Russian Federation
Assistant, PhD.
Moscow.
Competing Interests: The authors declare no conflict of interests.
V. I. Privalov
Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences
Russian Federation
Competing Interests: The authors declare no conflict of interests.
Russian Federation
Senior research assistant, PhD.
Moscow.
Competing Interests: The authors declare no conflict of interests.
A. A. Prokopov
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Russian Federation
Competing Interests: The authors declare no conflict of interests.
Russian Federation
Professor, Doctor of Chemical Sciences, Head of the Department of general and bioorganic chemistry.
Moscow.
Competing Interests: The authors declare no conflict of interests.
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Review
For citations:
Mitronin A.V., Srebnaya E.A., Privalov V.I., Prokopov A.A. High resolution-1Н NMR spectroscopy of oral liquid in young patients with wedge-shaped lesions. Endodontics Today. 2020;18(4):20-25. (In Russ.) https://doi.org/10.36377/1683-2981-2020-18-4-20-25
