The analysis of the microbial flora of root canals with chronic ulcerative pulpitis at the stage of endodontic treatment
was carried out. Antibacterial and anti-inflammatory efficacy in the preparations at endodontic treatment of root
canals was studied. Clinical studies of 83 patients showed that the analysis of microbial flora in the content of root
canals in patients with ulcerative pulpitis allowed identifying associations of two to nine species of bacteria, which
mainly referred to microaerophilic or obligate-anaerobic species. Variations of species composition of virulent microflora
at the stages of endodontic treatment were established. With the use of calcium hydroxide decontamination
efficacy of antibacterial root canal system increases twice, while with the use of copper-calcium hydroxide it increases
four times.

In the given work in gomogenates pulps of a constant teeth have been studied changes in the maintenance osteocalcin,
annexin V, alkaline phosphatase at a chronic pulpitis. It has been revealed that in a pulp of a tooth at an inflammation decrease
in quantity osteocalcin, alkaline phosphatase and increase in the maintenance annexin V is observed. The received
results testify to inhibition of education reparatived dentin in a pulp of a teeth at a chronic pulpitis.

Experiments on the pulp of rats teeth have shown that these preparations for a direct covering stimulate the formation of
replaceable hard connecting tissue and prevent the diffusion inflammation on the area of root pulp. Clinical tests have shown high
efficiency of the method of vital amputation of tooth pulp in treating pulpitis.

Basing on the lab and clinical material the benefits of the self-adapted rotary files in root canals with complex anatomical
shape are demonstrated.

This is a case study of treatment of a patient with combined pathology. After the
examination, it was diagnosed: «chronic apical periodontitis of teeth 1.1, 1.2, chronic
gingivitis of teeth 1.1, 1.2.» The treatment plan and the course of treatment by visits
are described in details. During the whole period of treatment the patient used a temporary
cosmetic and functional prostheses, which allowed her to avoid disability and
not to violate her usual lifestyle. As a result of the treatment the recovery has been
achieved. Cosmetic result was rated as positive and fully satisfied the requirements of
the patient.

At the heart of contemporary approaches to endodontic treatment of teeth, of course,
lies the teeth-saving technologies. The paper described the basic aspects of modern endodontics
with references to world literature, introduces the concept of endodontic treatment
of teeth in one visit, which the authors believe must now become the standard quality
of endodontic treatment. The basis of the work is proposed by the author the protocol of
apical periodontitis treatment in one visit.

The study included evaluation of the effect of ionizing ionization in modes up to 110 in vitro and Grey to 70 Grey in vivo on
the microstructure and mechanical properties of dentin of teeth to create the algorithm of endodontic treatment of patients
with radiation therapy of tumors of the maxillofacial region in history.
Structural differences between all groups of the coronal dentin was not revealed. In samples of root dentin were found
in part of sclerosal dentin with a decrease in the diameter of dentinal tubules. Significant differences between the mechanical
strength of the coronal dentin irradiated at a therapeutic dose of 70 Grey as in vitro, and in vivo from an intact missing.
Whereas a further increase in radiation dose, a slight decrease in strength. A deviation in the mechanical properties of the
root dentin (70 Grey in vivo) from the root of intact dentin.

By means of histologic, electron-microscopic and morphometrical methods it is established, that at odontogenic sinusitis
caused by deducing root canal filling material, develop considerable changes in epithelial layer and stroma. On early terms
(till 1 year) stay root canal filling in cilliar cells occur changes of cilliar device, structure infringement of cilia and increase in
microfibers that testifies to infringement mucocilliar transport system At a long finding root canal filling in sinus epithelium
is exposed single-layered metaplasia, occurs dedifferent change of epithelial cells. The basic signs of endocellular reorganisation
of such cells are decrease in squirrels-synthetic and plastic functions.

48 volunteers (20-31 years) were evaluated to estimate the occurrence of positive aspiration during intraceptal anesthesia,
comparing it with the level of pain threshold in target tooth.
Intraceptal anesthesia of lower premolars was introduced by single injection of 0.4 ml 4% articaine with 1:100,000 epinephrine
by computer syringe of QuickSleeper. Each injection was monitored by electrotest before and after 1-2, 5, 10 and
15 min. At the same time the monitoring of blood pressure and heart rate was performing.

The aim of research was the study of stomatological status and effectiveness of endodontic treatment in the populalion
of N.city. The analysis of 492 patientg at the age of 18-74 years in x-ray dental clinic was examined. Due to the examination
results, the optimal level of cemented rout canals in observed patients was revealed in 51% of cases. Statistically significant
age differences of growth in endodontically treated female teeth are from 30-40 till 45-59 years, and from 60 years in men.
Clinical effectiveness of endodontical treatment was 64%. The most common mistake in the rout canals failed cementing is
afalse obturation meeting over 50% cases.

One of the source of the bad quality endodontic treatment leading to the development of the chronical periapical lesions
may be missed and unfilled root channel. Premolars are teeth with multiple root canal system. Authors show that inflammatory
complications in premolars happen even often than in molars. In this review teeth (pemolars) investigation method
helping in acessesory root canal detection is offered and cases of the endodontic treatment of the premolars with multiple
root canals are described.

Group of 100 dental patients aged from 70 to 86 yrs (40 female and 60 male) medical and dental care in the hospital affiliated
to Board of Affairs of the President of Russian Federation was checked medically and dentally. Cardiovascular diseases
and endocrine pathology was revised as the medical history. Dental inspection involved dental clinical and radiological assessment
with recording the status of each tooth in accordance with international epidemiological conventions. Teeth with
endodontic pathology (primary or in root-canal treated teeth) were recorded particular.
In mean number of DMFT was over 19 in studied group. Dental Treatment degree was higher than 80% (based on «decayed
teeth/filled teeth» ratio) and higher than 90% (based on «decayed teeth/missing+filled teeth» ratio). The occurrence
of Filled Teeth was dominating over Missed Teeth. The occurrence of Endodonticly compromised teeth exceeded 48% in the
mean number of DFT. Positive correlation between mean number of DMFT and «decayed teeth/filled teeth» ratio suggests
the need of the in-time dental treatment of incipient decay lesions in elderly patients. Epidemiological data of the study suggest
the importance of developing special oral health inspection and treatment protocols for elderly patients.

We studied the comparative quality of root canal obturation with lateral condensation of gutta-percha using various sealers
and with different mechanical preparation of root canal. We evaluated the adhesion of sealers of different type to root canal
dentin. Using scanning electron microscopy varying degree of penetration of materials into dentinal tubules is revealed.

Determined the relative effectiveness of antibacterial poviargol. Proved the possibility of the influence of silver-containing
funds for extracellular DNA in the experiment. According to the classification of Valhauzer and Fisher poviargol assigned to the
antiseptic with a high degree of activity against antibiotic-resistant microorganisms.