Our Journal turns 20 years old in 2021.
The first issue of the journal was published in September 2001. At the origins of the journal's formation was Doctor of Medical Sciences, Professor A.M. Solovyova. From 2001 to 2008, only 2 issues were published per year. In 2005-2006, it experienced difficulties - it did not appear, and since 2009 it again began to publish and come out 4 times a year. From 2010 to the present, the editor-in-chief is Professor A.V. Mitronin. Our journal "Endodontics today" was conceived as a source of information about the state of endodontic science and practice in the world and as a channel of communication between specialists interested in endodontics. The title of the journal is intended to emphasize the concept of the journal, on the pages of which scientific and practical materials are published, reflecting the achievements of domestic and foreign authors on the problems of endodontics. Later, the expert council of the Higher Attestation Commission recommends reflecting on the pages of publications a wide research material on clinical dentistry of all profiles. Further, the editorial board of the journal included employees, professors of leading medical universities in Russia and foreign dental higher schools. It is pleasant to note that young specialists actively interested in therapeutic dentistry and modern endodontics appear on the pages of the journal and on scientific and practical domestic and foreign forums.
I would like to thank the editorial board, directorate and employees of the publishing house ENDO PRESS LLC of the Endodontics Today journal for their conscientious and necessary work. The "Endodontics Today" Journal is recommended by the Dental Association of Russia to reflect materials on topical problems of dental care for the population. The scientific and practical journal covers new technologies in improving the complex prevention, diagnosis, treatment and rehabilitation of patients with dental diseases. The pages of the journal are open to dentists, scientific researchers of medical universities in all regions of the Russian Federation and foreign countries. From 2010 to the present, the journal "Endodontics Today" has consistently been included in the list of leading peer-reviewed scientific journals and publications of the Higher Attestation Commission of the Ministry of Education and Science of Russia, in which the main scientific results of dissertations for the degree of Doctor and Candidate of Sciences should be published.
Sincerely.
Editor-in-chief of the journal "Endodontics today", Head of the Department of Cariesology and Endodontics, Dean of the Faculty of Dentistry, Moscow State Medical University. A.I. Evdokimova, Honored Doctor of the Russian Federation, member of the International Federation of Endodontic Associations (IFEA), member of the European Endodontic Society (ESE)
Doctor of Medical Sciences, Professor Mitronin A.V.

I congratulate you and all the staff of the editorial staff of the journal on the 20th anniversary. The journal "Endodontics Today" is included in the list of peer-reviewed scientific journals and publications of the Higher Attestation Commission of the Ministry of Education and Science of the Russian Federation, in which the main provisions of dissertations for the degree of Doctor and Candidate of Sciences should be published.
The journal reflects the state of medical and dental science and practice in Russia and the world in the field of dentistry and the section of therapeutic dentistry - endodontics on the basis of fundamental research of an applied nature. Recommended by the Dental Association of Russia to reflect materials on topical issues of providing dental care to the population.
The high scientific and practical potential of the editorial office allows the journal to be in leading positions among the periodicals of journals in the field of dentistry. The pages of the journal continue to be open to dentists, scientific researchers of medical universities in all regions of the Russian Federation, countries of the near and far abroad.
President of the Russian Dental Association
Doctor of Medical Sciences, Professor D.A. Trunin 

The "Endodontics Today" journal is a source of scientific and practical research in the field of conservative dentistry, endodontics in Russia. The journal rationally sets itself the task of helping those who are interested in the problems of endodontics, helps them better navigate the current state and the latest trends in its development. The results of modern scientific research make it possible to expand the possibilities of complex diagnostics and treatment of dental diseases. Works reflecting the achievements of domestic and foreign authors are published on the pages of a respected journal. I wish the journal to continue to contribute to the improvement of the professional skills of dentists, to preserve and strengthen the health of the population. New creative successes and a wide audience of readers.
Rector of Moscow State University of Medicine and Dentistry A.I. Evdokimova, Honored Doctor of the Russian Federation, Chief Freelance Dentist of the Russian Federation, President of the Society of Physicians of Russia, Academician of the Russian Academy of Sciences
Doctor of Medical Sciences, Professor O.O Yanushevich

Endodontics in conservative dentistry in Russia is one of the most progressively developing areas. More and more doctors are mastering modern technologies in dentistry and are engaged in scientific research. In 2010, in Athens, the Russian Endodontic Association joined the International Federation of Endodontic Associations (IFEA), and in 2011 in Italy (Rome) - the European Endodontic Society (ESE), and since then Russian specialists annually participate in all congresses, receiving and sharing with colleagues the latest achievements in the world of endodontics. There is now the world and its own experience of scientific and practical research in the Journal articles. On behalf of the Board of the Endodontic Section, I congratulate the "Endodontics Today" Journal, the editorial staff on the 20th anniversary.
President of the StAR Endodontic Section
Doctor of Medical Sciences, Professor I.M. Rabinovich 

The scientific and practical journal "Endodontics today" covers the state of the dental school on the issues of modern endodontics, medical and dental science and practice in Russia and the world. Specialists master modern technologies and engage in scientific research. Interest is aroused by the success of Russian specialists in the comprehensive study of dental diseases in combination with the general pathology of the patient's body, which will improve their quality of life.

I congratulate the editors of the magazine "Endodontics today" on the anniversary – 20 years!

Direktor of Center of Oral Health; Chef of the Department of Restorative Dentistry, Periodontology and Endodontology, University of Greifswald Honorary Professor of Moscow State University of Medicine and Dentistry
Professor, Dr. Georg Meyer

Aim. To establish the association between the presence of chronic infection in oral cavity and the severity of SARSCoV-2 infection.
Materials and methods. The study was conducted among 30 people aged between18 and 22 who had had coronavirus infection from mild to severe cases. The assessment of oral health was carried out with main and additional examination methods, CFE index, PMA index, Greene, Wermillion oral hygiene index.
Results. In group 1, the average value of CFE index was 4.2, in the second group – CFE index was twice higher at 7.8. PMA index in patients of group 2 was significantly higher (p> 0.01) and was at the level of 41.5%. In group 1, the PMA index was 13.3%. It was found that 17% of the respondents in the control group and 70% patients in the experimental group had an episodic exacerbation of dental diseases during COVID-19.
Conclusions. The data obtained indicates a correlation between oral diseases and the severity of COVID-19. It is necessary to consider that chronic infection in the oral cavity as well as poor oral hygiene can act as a risk of complications of viral infections, in particular, of COVID-19.

Relevance. The reason for the study was our histological specimen with intrapulpal dye injection from the monograph "Anesthesia in Endodontics". Outside the pulp chamber, in the root canal, the ink is diffusely distributed throughout the vessels. There was a hypothesis about the vascular nature of intrapulpal injection.
Aim. Тo prove vascular mechanism intrapulpal injection.
Materials and methods. A randomized prospective pilot study was performed in 15 patients (9 men, 6 women) with 15 teeth vital pulpectomy. Traditional anesthesia conducted articaine 4% with epinephrine 1:100 000. When accessed in the pulpintroduced drop the same anesthetic. Heart rate was determined after 30 seconds for 3 minutes pulse oximeter MD 300.
Results. There was expressed vascular reaction to intrapulpal introduction anesthetic with epinephrine. It has resulted in a sharp increase in pulse rate by an average of 11.3 beats /min, return to the original level after 3 minutes.
Conclusions. Based on the results obtained, we assume the vascular-venous nature of intrapulpal anesthesia.

Aim. To determine possible alternative algorithms for root canal disinfection through the combined use of chemical and physiotherapeutic irrigation techniques under in vitro conditions.
Materials and methods. Single-root teeth removed according to orthodontic indications were used as a substrate for the formation of a biofilm. The formation of a mixed biofilm is carried out in several stages, successively introducing the following strains: Streptococcus sanguinis; Fusobacterium nucleatum; Porphyromonas gingivalis. Cultivation was carried out under fluid conditions under anaerobic conditions, for 168 hours. After the cultivation, the teeth were treated using: a solution of chlorhexidine bigluconate 2%; a solution of sodium hypochlorite 3%; photodynamic exposure with Fotoditazin photosensitizer; 1.0% sodium hypochlorite solution in combination with photodynamic exposure. The results were evaluated using scanning electron microscopy.
Results. The results of scanning electron microscopy revealed differences between the samples of the control group and the comparison group. The number of bacterial cells was significantly lower in the comparison group than in the control group, however, in all samples, the presence of microbial biofilm sites was noted with varying degrees of severity. In the samples where standard concentrations were used, there was a change in the ultrastructure of the walls of the dentine tubules with its partial destruction and obturation by its own fragments of the walls with the presence of microbial cells. When using the photodynamic effect of destruction was not observed. The microbial landscape had a similar species composition, and more fragments of biofilm and individual cells were observed only in the case of PDT without a combination with an antiseptic.
Conclusions. A comprehensive approach to endodontic treatment using photodynamic therapy together with antiseptic solutions in low concentrations allows us to achieve the best effect of pathogen eradication in comparison with the standard chemomechanical method.

Adhesive post-endodontic treatment does not yet have a generally accepted clinical protocol. We perform this procedure in our clinical practice since 2006. We have developed a clinically successful protocol. Tissues and materials which relate to the the procedure are described following available research. Protocol is described in step-by-step.

Reducing the orthodontic treatment duration is an important issue, especially for adult patients who want to complete treatment faster due to social or aesthetic reasons. In addition, an increase in the duration of orthodontic treatment has a number of side effects, therefore, orthodontists and patients are interested in the use of techniques that can accelerate the movement of teeth. Shorter treatment times can be achieved through a combination of orthodontic and surgical or non-surgical techniques.
Aim. To systematically evaluate scientific data on the effectiveness and side effects of surgical and non-surgical methods in accelerating orthodontic treatment in situations with the removal of premolars and subsequent closure of the post-extraction spaces.
Materials and methods. Electronic search of articles was carried out using search engines and databases: Cyberleninka, eLIBRARY, Google Scholar, Pub Med, SCOPUS. The publication date criterion was selected from January 2010 to January 2021. Articles included in the systematic review had to meet the following inclusion criteria: controlled clinical trials and randomized controlled clinical trials conducted in humans and published in the last 11 years in English language. The systematic review included and analyzed 15 full-text articles.
Result. According to the systematic review, the speed of movement of teeth increases 2 times with corticotomy, and 1.5 times with piezocorticotomy, which is consistent with the data of other studies. At the same time, the effectiveness of the movement remains for no more than 2 months after the intervention.
Conclusions. The corticotomy procedure reduces the treatment time in comparison with traditional methods by 30-50% (6-8 months). The investigated techniques did not have a significant effect on the depth of probing, the level of attachment, on the density of bone tissue, rotation and inclination of the moved teeth. Since no complications were identified for 2-4 months of observation, further studies are required to assess long-term results in the long term.

Aim. Article is to detail the positive and negative aspects associated with the creation of a glide path with various types of endodontic instruments.
Materials and methods. During a systematic review of the literature, Russian – and English-language publications were studied in the electronic databases PubMed, Google Scholar. Articles, the content of which concerns the methods of creating a glide path, as well as possible complications were included in analysis.
Results. 60 articles were reviewed during the review. After analyzing the literature according to the inclusion and exclusion criteria, the total number of publications has become 32.
Conclusions. According to the studied literature, it can be said that the glide path provides a predictable behavior of rotary tools and it is a recommended condition for achieving the success of endodontic treatment at the stage of canal mechanical treatment and preventing iatrogenic complications.

Relevance. To date, the prescription of nonsteroidal anti-inflammatory drugs for the treatment of complicated forms of caries, accompanied by a pronounced pain syndrome, is still needed. The main criteria to be met by NSAIDs used by patients are: adequacy of clinical situation, safety, effectiveness. However, if the choice of therapeutic agent is made without taking into account the accompanying somatic pathology, there is a risk of harm to the patient's health, both on the recommendation of the attending physician, and when the patient himself using the drug. The use of NSAIDs in medical practice is often fraught with serious adverse events (AEs), primarily from the gastrointestinal tract (GIT), cardiovascular system (CVS), etc. The task of the doctor, who prescribes NSAIDs to the patient, is to minimize the negative effects of these drugs on digestive and cardiovascular system of the patient while achieving the optimal analgesic and anti-inflammatory effects.
Aim. To study the peculiarities of non-steroidal anti-inflammatory drugs in the treatment of complicated caries in patients with concomitant somatic pathology.
Materials and methods. Retrospective review of domestic and foreign publications, questionnaire survey of dentists concerning prescribed NSAIDs, and generalized recommendations for prescribing these drugs taking into account the features of general medical diseases were carried out.
Results. Basing on literature data and own clinical observations, the most frequently prescribed drugs for pain reaction relief in patients with complicated forms of caries were singled out and recommendations for prescription of NSAIDs in patients with generalosomatic diseases were suggested.
Conclusions. This work offers recommendations for the use of NSAIDs in dental patients with concomitant somatic pathology.

This case report describes the 11 tooth old restoration removal and new direct composite restoration placement(Enamel Plus, Micerium S.p.A, Avengo, Ge, Italy). Direct anterior restorations are today a very nice, minimal invasive and cheap opportunity to restore one or more teeth. With the use of modern materials, the right techniques and protocols we can obtain mimetic restorations that they can work on the mouth of the patient for a long time.

One of the most common methods of dental treatment in a minimally invasive concept is a direct restoration of carious damaged teeth or teeth with dental trauma. In this article represents a clinical case of old unsatisfactory restorations replacement in teeth 36, 37 followed by restoration of hard tissue class II defects using direct composite restoration taking into account aesthetic and biomechanical aspects.

A number of researchers note the fact that today, in more than 5.7% of the teeth in patients over 40-45 years old with apical periodontal lesions, during a comprehensive examination, lesions of the marginal periodontium are also diagnosed.
Materials and methods. The success of endodontic treatment of such teeth with the use of traditionally used polymer sealers is extremely low. Pathology develops due to a mixed apical-periodontal microflora. The use of bioceramic sealers has been reported to significantly improve the prognosis for endodontic intervention. Bioceramics inherently is the most biocompatible material and consists of aluminum oxide, zirconium dioxide, bioactive glass, glass ceramics, composite components and coatings, hydroxyapatite and resorbable calcium phosphates.
Results. This article presents clinical cases of successful endodontic treatment of the main types of combined apical and marginal pathology. 9-11 months after treatment, the diagnosed signs of perio-dontal and periapical pathology are not determined.
Conclusions. Based on the results obtained, the optimal method that ensures a successful treat-ment result for this pathology in one visit, often without subsequent surgical manipulations, is an ade-quate endodontic mechanical intervention with subsequent obturation of the root canals with a bioc-eramic sealer, which is confirmed by the literature data.

Relevance. Currently, researchers pay close attention to the study of chronic diseases that have a direct or indirect impact on the state of the patient’s dental status. It is known that chronic inflammatory diseases of the oral organs are, often simultaneously, permanent foci of infection that affect the state of other systems and organs. The general list of such diseases includes: chronic gingivitis, chronic generalized periodontitis, glossitis, gingivostomatitis.
Aim. The aim of the study was to study the effectiveness of complex conservative therapy, including natural therapeutic factors of Crimea, in patients with chronic inflammatory diseases of the oral organs, occurring against the background of somatic pathology.
Materials and methods. The objects of the study were periodontal tissues in 70 people with chronic generalized periodontitis (CGP) and gingivostomatitis, occurring against the background of gastrointestinal (GI) diseases.
Results. The results obtained indicate that complex treatment with local application of hydrotherapy named “PhytoBiol” and thermal Saka mineral water (in a dilution of 1:4), combined with periodontal dressings according to the recipe proposed by us, cause persistent remission of these diseases, contribute to the improvement of periodontal tissues and oral mucosa. Thus, complex treatment of inflammatory diseases of periodontal tissues in patients in the main group (n = 35) led to long-term remission in 82.33% of cases, while in the control group the result was 69.5% (at p < 0.05).
Conclusions. The positive results, which were obtained, give grounds to recommend the proposed complex of treatment and prevention of exacerbations of this chronic disease for use in practical health care.

Analysis to identify the relationship between the unfavorable living environment and congenital malformations of dental anomalies in the children's population of Kizlyar (the environment of disadvantage) and Khasavyurt (the environment of well-being).
Materials and methods. To identify the main causes of the appearance of congenital clefts, we conducted a survey of 125 parents of children with questions included in the questionnaire: Full name, gender, date of birth, address, nationality, what is the pregnancy, whether the mother took medication in the first 3 months of pregnancy, the level of hemoglobin and infectious diseases during pregnancy, whether there were cases (heredity).
Results. Dates from 125 medical histories for 2017-2019 with different types of congenital cleft lip and palate showed that in 59 children, the chemical factor was the cause of the disease, since one of the parents worked in agriculture or an industrial enterprise with a chemical bias, for genetic reasons, 15 children; viral colds-22 children, anemia of pregnant women-25 cases. 35 patients with the chemical factor were born in Kizlyar, only 5 patients from Khasavyurt.
Conclusions. The high level of morbidity of the child population in Kizlyar indicates the need to develop and implement recommendations for the organization of preventive and medical-dental care for adolescents and children from an early age.